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Introduce the beauty & wisdom of the rainforest to your daily routine.

anti-aging serums for fine lines, wrinkles, reduce dark circles

Harvested from ancient, wild botanicals native to the Amazon and refined by expert dermatologists, our patented herbal extract, ac-11®, works with the skin's natural processes to repair it at the DNA level.

anti-aging serums for fine lines, wrinkles, reduce dark circles

Dr. Vincent Giampapa, Co Founder

“Our patented technology is proven to rejuvenate your skin at the DNA level."


ac-11® is an all-natural, safe and effective aqueous extract of Uncaria tomentosa, a medicinal plant indigenous to the Amazon rainforest. ac-11® is manufactured using a proprietary ultra-filtration process that produces a low weight (less than 10,000 Daltons) bioavailable, scientifically indole alkaloid free (less than 0.05 ppm) extract. Our patented process standardizes Carboxy Alkyl Esters (CAEs), the biologically active ingredient in ac-11®, to minimum 8%. Our primary research has demonstrated ac-11®’s natural ability to help the body repair its own DNA. Additional studies have also demonstrated ac-11®’s ability to: reduce proinflammatory cytokines, encourage cell apoptosis (cellular death) of damaged cells, enhance the immune system and decrease the rate of telomere truncation. ac-11® has both oral use and topical applications. 

Optigenex harvests ac-11 under the authority of the Brazilian Institute of Environment and Renewable Natural Resources (IBAMA). Authorization is granted through an ongoing sustainable management project directed by the government and based upon local availability.

The active ingredients in the day, night and eye formulas are all natural. A small percentage of each product consists of preservatives and equalizers that are derivatives of natural ingredients. These commonly used constituents are essential to providing a balanced and stable product and can be found in luxury creams on the market today.